The pedestrian - an 8 year old girl - was treated by paramedics but was sadly pronounced dead at the scene.
A 24-year-old man was arrested on suspicion of causing death by dangerous driving. He remains in custody for questioning.
Monton Road is currently closed between Cavendish Road and Half Edge Lane.
Enquiries are still ongoing.
Police Sergeant Lee Westhead, of GMP’s Serious Collision Investigation Unit, said:
Anyone with information should call GMP’s Serious Collision Investigation Unit on 0161 856 4741 quoting reference number of 09/11/2018, or the independent charity Crimestoppers, anonymously, on 0800 555 111.